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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPE
All Species:
12.12
Human Site:
S1427
Identified Species:
22.22
UniProt:
Q02224
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02224
NP_001804.2
2701
316415
S1427
E
I
E
M
L
G
L
S
K
R
L
Q
E
S
H
Chimpanzee
Pan troglodytes
XP_001170168
2701
316707
S1427
E
I
E
M
L
G
L
S
K
R
L
Q
E
S
H
Rhesus Macaque
Macaca mulatta
XP_001110512
2701
316828
S1427
E
I
E
M
L
R
L
S
K
R
L
Q
E
S
H
Dog
Lupus familis
XP_852631
1216
141588
I106
S
Q
D
Y
L
G
V
I
P
R
A
I
H
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6RT24
2474
286506
Q1361
T
L
Q
V
E
C
T
Q
L
K
E
D
A
R
R
Rat
Rattus norvegicus
Q7TSP2
1385
159522
T275
G
S
E
R
Q
K
D
T
H
A
E
G
M
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420670
2150
248600
I1040
M
T
E
E
L
K
N
I
T
S
E
R
D
C
L
Frog
Xenopus laevis
NP_001080954
2954
339950
T1620
E
E
K
I
L
L
L
T
E
E
L
H
Q
K
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524993
2013
231091
M903
T
S
H
V
E
E
S
M
R
S
S
G
I
S
S
Honey Bee
Apis mellifera
XP_001121311
1418
164919
R308
C
T
L
S
F
A
Y
R
A
K
S
V
K
N
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781622
2537
290578
E1358
A
N
L
L
Q
E
T
E
E
L
R
E
E
K
N
Poplar Tree
Populus trichocarpa
XP_002308893
1247
142380
P137
D
I
N
D
L
L
A
P
E
H
R
K
L
Q
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187629
1348
152938
K238
A
G
S
E
R
A
A
K
T
G
A
E
G
V
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.7
37.8
N.A.
60.5
21.2
N.A.
N.A.
37.1
31
N.A.
N.A.
26.1
24.8
N.A.
25.5
Protein Similarity:
100
99.2
98
42
N.A.
75
35.7
N.A.
N.A.
55
52.2
N.A.
N.A.
45.6
37.8
N.A.
48.8
P-Site Identity:
100
100
93.3
20
N.A.
0
6.6
N.A.
N.A.
13.3
26.6
N.A.
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
93.3
33.3
N.A.
26.6
13.3
N.A.
N.A.
26.6
60
N.A.
N.A.
20
20
N.A.
33.3
Percent
Protein Identity:
23.9
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
34.6
N.A.
N.A.
37.6
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
16
16
0
8
8
16
0
8
0
0
% A
% Cys:
8
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
8
8
0
0
8
0
0
0
0
8
8
8
0
% D
% Glu:
31
8
39
16
16
16
0
8
24
8
24
16
31
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
0
24
0
0
0
8
0
16
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
8
8
0
8
8
0
24
% H
% Ile:
0
31
0
8
0
0
0
16
0
0
0
8
8
0
16
% I
% Lys:
0
0
8
0
0
16
0
8
24
16
0
8
8
16
8
% K
% Leu:
0
8
16
8
54
16
31
0
8
8
31
0
8
0
16
% L
% Met:
8
0
0
24
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
8
8
0
0
0
8
0
0
0
0
0
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
16
0
0
8
0
0
0
24
8
8
0
% Q
% Arg:
0
0
0
8
8
8
0
8
8
31
16
8
0
16
16
% R
% Ser:
8
16
8
8
0
0
8
24
0
16
16
0
0
31
8
% S
% Thr:
16
16
0
0
0
0
16
16
16
0
0
0
0
0
8
% T
% Val:
0
0
0
16
0
0
8
0
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _